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Nor-Cerpegin

Nor-Cerpegin is an analog of Cerpegin. Cerpegin, a pyridinone-fused c-lactone, is an inhibitor of 20S proteasome. Cerpegin can be used as a tranquillizer, anti-inflammatory, analgesic and antiulcer[1][2].

Product Specifications

CAS Number

[145887-88-3]

UNSPSC

12352005

Target

Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nor-cerpegin.html

Smiles

O=C1OC(C)(C)C(C=CN2)=C1C2=O

Molecular Formula

C9H9NO3

Molecular Weight

179.17

References & Citations

[1]Anna Hovhannisyan, et al. New C (4) - and C (1) -derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform. Bioorg Med Chem Lett. 2014 Mar 15;24 (6) :1571-80.|[2]K. Sivakumar, et al. Structure of cerpegin, a new alkaloid. Acta Cryst. (1990) . C46, 839-841.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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