Nor-Cerpegin
Nor-Cerpegin is an analog of Cerpegin. Cerpegin, a pyridinone-fused c-lactone, is an inhibitor of 20S proteasome. Cerpegin can be used as a tranquillizer, anti-inflammatory, analgesic and antiulcer[1][2].
Product Specifications
CAS Number
145887-88-3
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nor-cerpegin.html
Smiles
O=C1OC(C)(C)C(C=CN2)=C1C2=O
Molecular Formula
C9H9NO3
Molecular Weight
179.17
References & Citations
[1]Anna Hovhannisyan, et al. New C (4) - and C (1) -derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform. Bioorg Med Chem Lett. 2014 Mar 15;24 (6) :1571-80.|[2]K. Sivakumar, et al. Structure of cerpegin, a new alkaloid. Acta Cryst. (1990) . C46, 839-841.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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