Ferulic acid-13C3

Ferulic acid-13C3 is the 13C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

Product Specifications

CAS Number

[1261170-81-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; FGFR; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ferulic-acid-13c3.html

Purity

98.3

Solubility

10 mM in DMSO

Smiles

O=[13C](O)/[13CH]=[13CH]/C1=CC=C(O)C(OC)=C1

Molecular Formula

C7 13C3H10O4

Molecular Weight

197.16

Precautions

H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Yang GW, et al. Ferulic Acid Exerts Anti-Angiogenic and Anti-Tumor Activity by Targeting Fibroblast Growth Factor Receptor 1-Mediated Angiogenesis. Int J Mol Sci. 2015 Oct 12;16 (10) :24011-31.|[3]Zeni AL, et al. Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: evidence for the involvement of the serotonergic system. Eur J Pharmacol. 2012 Mar 15;679 (1-3) :68-74.