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CFD Recombinant Rabbit Monoclonal Antibody [JE65-08]

Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein which in humans is encoded by the CFD gene. Factor D is involved in the alternative complement pathway of the complement system where it cleaves factor B. The protein encoded by this gene is a member of the trypsin family of serine proteases secreted by adipocytes into the bloodstream. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. Factor D is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Adipsin antibody Adipsin/complement factor D antibody Adn antibody C3 convertase activator antibody CFAD_HUMAN antibody CFD antibody Complement factor D antibody complement factor D preproprotein antibody D component of complement antibody DF antibody FactorD antibody PFD antibody Properdin factor D antibody

Abbreviation

CFD, DF, PFD

Swiss Prot

P00746 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human CFD aa 54-253 / 253.

Isotype

IgG

Clone

JE65-08

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, IF-Tissue

Positive Control

THP-1 cell lysate, A549 cell lysate, U-937 cell lysate, Human serum lysate, Human plasma lysate, THP-1, human kidney tissue, mouse kidney tissue, rat kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:5,000 ;IF-Tissue: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 27 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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