Changnanic acid

Changnanic acid (schisandrin) is a triterpene compound with potential anti-tumor effects. Changnanic acid exhibits moderate cytotoxic activity against human tumor cell lines Bel-7402, MCF-7 and HL-60, with IC50s of 100 μM, 100 μM and 50.51 μM respectively[1].

Product Specifications

CAS Number

[136040-44-3]

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/changnanic-acid.html

Purity

96.79

Solubility

10 mM in DMSO

Smiles

OC(CC[C@]12[C@@]3(C2)[C@](C=C[C@H]1C(C)=C)([H])[C@]4([C@](CC3)([C@@](CC4)([H])[C@H](C)CC/C=C(C)\C(O)=O)C)C)=O

Molecular Formula

C30H44O4

Molecular Weight

468.67

References & Citations

[1]Wang W, et al. New triterpenoids from Kadsura heteroclita and their cytotoxic activity. Planta Med. 2006 Apr;72 (5) :450-7.|[2]Wang W. et al. New triterpenoids from Kadsura heteroclita and their cytotoxic activity. Planta Med. 2006 Apr;72 (5) :450-7.