12-Dehydrogingerdione
12-Dehydrogingerdione is an inhibitor of NO Synthase. 12-Dehydrogingerdione signi cantly inhibits LPS-stimulated production of NO, IL-6 and PGE2 in Raw 264.7 cells[1].
Product Specifications
CAS Number
99742-05-9
Product Name Alternative
12-DHGD
UNSPSC
12352005
Target
Interleukin Related; NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/12-dehydrogingerdione.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCC(/C=C(O)/C=C/C1=CC(OC)=C(C=C1)O)=O
Molecular Formula
C23H34O4
Molecular Weight
374.51
References & Citations
[1]Han YA, et al. Anti-inflammatory effects of the Zingiber officinale roscoe constituent 12-dehydrogingerdione in lipopolysaccharide-stimulated Raw 264.7 cells. Phytother Res. 2013 Aug;27 (8) :1200-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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