BuChE-IN-12
Product Specifications
UNSPSC Description
BuChE-IN-12 is a selective BuChE inhibitor (IC50=0.52 µM) that acts via affecting CAS and PAS sites and has potential effects against oxidative stress. BuChE-IN-12 can be used in the study of Alzheimer's disease[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/buche-in-12.html
Smiles
CC1=CC=C(NC2=C3C=CC=CC3=NC(NC4=CC=C(C)C=C4)=N2)C=C1
Molecular Weight
340.42
References & Citations
[1]Sadeghian, et al. Synthesis, biological evaluation, molecular docking, and MD simulation of novel 2, 4-disubstituted quinazoline derivatives as selective butyrylcholinesterase inhibitors and antioxidant agents. Scientific Reports 14.1 (2024): 15577.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162671/BuChE-IN-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162671/
Clinical Information
No Development Reported
CAS Number
1363947-94-7
Curated Selection
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