Heparin-binding EGF-like Growth Factor

<strong>Heparin-binding EGF-like Growth Factor</strong>_x000D_ <strong>Catalog number:</strong> B2010304_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Heparin-binding EGF-like Growth Factor expressed in E. coli. This protein acts as a member of the epidermal growth factor (EGF) family of growth factors that stimulate growth and differentiation._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuHB-EGF; HBEGF; Diphtheria toxin receptor; DTR_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kim S, Graham MJ, Lee RG, Yang L, Kim S, Subramanian V, Layne JD, Cai L,_x000D_ Temel RE, Shih D, Lusis AJ, Berliner JA, Lee S. Heparin-binding EGF-like growth_x000D_ factor (HB-EGF) antisense oligonucleotide protected against hyperlipidemia-_x000D_ associated atherosclerosis. Nutr Metab Cardiovasc Dis. 2019 Mar;29(3):306-315._x000D_ _x000D_ 2: Dao DT, Anez-Bustillos L, Adam RM, Puder M, Bielenberg DR. Heparin-Binding_x000D_ Epidermal Growth Factor-Like Growth Factor as a Critical Mediator of Tissue_x000D_ Repair and Regeneration. Am J Pathol. 2018 Nov;188(11):2446-2456._x000D_ PMC6207098._x000D_ _x000D_ 3: Gaviglio AL, Knelson EH, Blobe GC. Heparin-binding epidermal growth factor-_x000D_ like growth factor promotes neuroblastoma differentiation. FASEB J. 2017_x000D_ May;31(5):1903-1915._x000D_ _x000D_ 4: Cramer ML, Xu R, Martin PT. Soluble Heparin Binding Epidermal Growth Factor-_x000D_ Like Growth Factor Is a Regulator of <i>GALGT2</i> Expression and_x000D_ <i>GALGT2</i>-Dependent Muscle and Neuromuscular Phenotypes. Mol Cell Biol. 2019_x000D_ Jun 27;39(14):e00140-19._x000D_ _x000D_ 5: Ma F, Li S, Hao H, Gao P, Dai Y, Himani C, Liu W, Gao X, Xiao X. Association_x000D_ of Heparin-binding EGF-like Growth Factor Polymorphisms With Necrotizing_x000D_ Enterocolitis in Preterm Infants. J Pediatr Gastroenterol Nutr. 2018_x000D_ Apr;66(4):e99-e102._x000D_ _x000D_ 6: Su Y, Luo H, Yang J. Heparin-binding EGF-like growth factor attenuates lung_x000D_ inflammation and injury in a murine model of pulmonary emphysema. Growth_x000D_ Factors. 2018 Dec;36(5-6):246-262._x000D_ _x000D_ 7: Liu Z, Skafar DF, Kilburn B, Das SK, Armant DR. Extraembryonic heparin-_x000D_ binding epidermal growth factor-like growth factor deficiency compromises_x000D_ placentation in mice. Biol Reprod. 2019 Jan 1;100(1):217-226._x000D_ _x000D_ 8: Raab G, Klagsbrun M. Heparin-binding EGF-like growth factor. Biochim Biophys_x000D_ Acta. 1997 Dec 9;1333(3):F179-99._x000D_ _x000D_ 9: Thönes S, Rother S, Wippold T, Blaszkiewicz J, Balamurugan K, Moeller S,_x000D_ Ruiz-Gómez G, Schnabelrauch M, Scharnweber D, Saalbach A, Rademann J, Pisabarro_x000D_ MT, Hintze V, Anderegg U. Hyaluronan/collagen hydrogels containing sulfated_x000D_ hyaluronan improve wound healing by sustained release of heparin-binding EGF-_x000D_ like growth factor. Acta Biomater. 2019 Mar 1;86:135-147._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30455099/">10: Ming YC, Chao HC, Chu SM, Luo CC. Heparin-binding epidermal growth factor-_x000D_ like growth factor (HB-EGF) protected intestinal ischemia-reperfusion injury_x000D_ through JNK and p38/MAPK-dependent pathway for anti-apoptosis. Pediatr Neonatol._x000D_ 2019 Jun;60(3):332-336.</a>_x000D_ _x000D_ <strong>Products Related to Heparin-binding EGF-like Growth Factor </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>