Met-Leu-MCA

<strong>Met-Leu-MCA</strong> <strong>Catalog number:</strong> MDP0281 <strong>CAS Number: </strong>58569-55-4 <strong>Sequence: </strong>L-Methionyl-L-Leucine 4-methylcoumaryl-7-amide <strong>Amount:</strong> 1 mg <strong>Molecular Weight:</strong> 419.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Cavicchioni G, Fraulini A, Falzarano S, Spisani S. Structure-activity relationship of for-L-Met L-Leu-L-Phe-OMe analogues in human neutrophils Bioorg Chem. 2006 Oct;34(5):298-318. 2: Kurt S, Ordu E. Effect of Met/Leu substitutions on the stability of NAD+-dependent formate dehydrogenases from Gossypium hirsutum Appl Microbiol Biotechnol. 2021 Apr;105(7):2787-2798. 3: Zhang M, Li M, Wang JH, Vogel HJ. The effect of Met-->Leu mutations on calmodulin's ability to activate cyclic nucleotide phosphodiesterase J Biol Chem. 1994 Jun 3;269(22):15546-52. 4: Asai M, Cano A, Talavera E, Zubieta M. IR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma mexicanum) Neuropeptides. 1988 Jul;12(1):41-2. 5: Jesaitis AJ, Gripentrog J, Voyich JM. Formyl Met-Leu-Phe-Stimulated FPR1 Phosphorylation in Plate-Adherent Human Neutrophils: Enhanced Proteolysis but Lack of Inhibition by Platelet-Activating Factor J Immunol Res. 2018 Jan 24;2018:3178970. 6: Notsu Y, Namiuchi S, Hattori T, Matsuda K, Hirata F. Inhibition of phospholipases by Met-Leu-Phe-Ile-Leu-Ile-Lys-Arg-Ser-Arg-His-Phe, C terminus of middle-sized tumor antigen Arch Biochem Biophys. 1985 Jan;236(1):195-204. 7: Ding R, Xu G, Feng Y, Zou L, Chao W. Lipopeptide PAM3CYS4 Synergizes N-Formyl-Met-Leu-Phe (fMLP)-Induced Calcium Transients in Mouse Neutrophils Shock. 2018 Oct;50(4):493-499. 8: Larsson LI, Stengaard-Pendersen K. Immunocytochemical and ultrastructural differentiation between Met-enkephalin-, Leu-enkephalin-, and Met/Leu-enkephalin-immunoreactive neurons of feline gut J Neurosci. 1982 Jul;2(7):861-78. 9: Bültmann BD, Allmendinger P, Raus RU, Melzner I, Haferkamp O, Eggers H, Gruler H. F-Met-Leu-Phe and echo 9 virus interaction with human granulocytes. Changes of cell membrane structure Am J Pathol. 1984 Jul;116(1):46-55. <a href="https://pubmed.ncbi.nlm.nih.gov/15147563">10: Fu H, Bylund J, Karlsson A, Pellmé S, Dahlgren C. The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8 Immunology. 2004 Jun;112(2):201-10. </a> <br><strong>Products Related to Met-Leu-MCA can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>