PROTAC BRD9 Degrader-6
PROTAC BRD9 Degrader-6 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders[1].
Product Specifications
CAS Number
[2676211-62-2]
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd9-degrader-6.html
Purity
98.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C(C3=CC(OC)=C(CN4CCC(CC4)CN5CCC6(CC5)CN(C6)C7=CC=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=C7)C(OC)=C3)=CN1C)C=C(N%10CCC%10)N=C2
Molecular Formula
C47H56N8O6
Molecular Weight
829.00
References & Citations
[1]Ruppel Sabine K, et al. Preparation of substituted naphthyridines for treating BAF complex-related disorders. United States, US20210230190 A1. 2021-07-29.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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