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(R) -Indeloxazine (benzenesulfonate)

(R) -Indeloxazine benzenesulfonate (AS1069562) is an orally active 5-HT and NE reuptake inhibitor, with IC50 values of 0.35 μM and 3.3 μM, respectively. (R) -Indeloxazine benzenesulfonate (AS1069562) possesses curative-like analgesic effect. (R) -Indeloxazine benzenesulfonate (AS1069562) might improve nerve function impairment via the amelioration of neurotrophic support[1][2].

Product Specifications

CAS Number

1623762-83-3

Product Name Alternative

AS1069562; (R) -YM-08054 (benzenesulfonate)

UNSPSC

12352005

Target

5-HT Receptor; Serotonin Transporter

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/r-indeloxazine-benzenesulfonate.html

Smiles

O=S(O)(C1=CC=CC=C1)=O.[C@@H]2(CNCCO2)COC3=C4C(C=CC4)=CC=C3

Molecular Formula

C20H23NO5S

Molecular Weight

389.47

References & Citations

[1]Nobuhito Murai, et al. AS1069562, the (+) -isomer of indeloxazine, exerts analgesic effects in a rat model of neuropathic pain with unique characteristics in spinal monoamine turnover. J Pharmacol Exp Ther. 2014 Mar;348 (3) :372-82.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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