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CD61 (25E11.), 1mg/mL

Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain) . The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ITGB3

Gene ID

3690

NCBI Gene ID

218040

UniProt

P05106

Swiss Prot

P05106

Host

Mouse

Species Reactivity

Human

Reactivity

CD61

Immunogen

Normal blood mononuclear cells activated by mixed lymphocyte reaction

Target Antigen

CD61

Clonality

Monoclonal

Clone

2500000000000

Type

Primary

Source

Animal

Origin

Animal

Field of Research

Cell adhesion

Positive Control

U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

105 kDa & 90 kDa

References & Citations

McMichael AJ et al. (eds) Leukocyte Typing III, Oxford University Press, Oxford, 1987. | Schlossman S. et al. (eds) Leukocyte Typing V, Oxford University Press, Oxford, 1995

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgM, kappa

Species

Mus musculus (mouse)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free

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