CD61 (25E11.), 0.2mg/mL
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain) . The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
CAS Number
9007-83-4
Synonyms
BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGB3
Gene ID
3690
NCBI Gene ID
218040
UniProt
P05106
Swiss Prot
P05106
Host
Mouse
Species Reactivity
Human
Reactivity
CD61
Immunogen
Normal blood mononuclear cells activated by mixed lymphocyte reaction
Target Antigen
CD61
Clonality
Monoclonal
Clone
2500000000000
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cell adhesion
Positive Control
U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
105 kDa & 90 kDa
References & Citations
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
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