Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CD6 (Negative Marker of T-regulatory Cells) (SPV-L14), CF640R conjugate, 0.1mg/mL

Selected Variant

BNC400402-500

Size: 1x 500 µL

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Product Specifications

CAS Number

9007-83-4

Synonyms

T12; TP120

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD6

Gene ID

923

NCBI Gene ID

744366

UniProt

P30203

Swiss Prot

P30203

Host

Mouse

Species Reactivity

Human, Mouse

Reactivity

CD6

Immunogen

CD8 cytotoxic T-cell clone

Target Antigen

CD6

Clonality

Monoclonal

Clone

SPV-L14

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow (verified) |Flow, surface (published) |Functional studies (published) |IF (published) |IF (verified)

Field of Research

Immunology

Positive Control

CCRF-CEM, Jurkat cells, Tonsil

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

90-130 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1987) 84: 3861-3865. (Flow, surface; IF) J Inv Dermatol (1994) 102(6): 833-837. (Flow, surface) J Immunol (2006) 177:1152-1159. (functional studies) Nat Immunol (2014) 15(4): 384-392. (functional studies)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF640R

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Neurofilament (NF-L) (NR-4), 0.2mg/mL
BNUB0303-100 1x 100 µL

Neurofilament (NF-L) (NR-4), 0.2mg/mL

Sign In for Pricing
View Details
Anti-SERINC2 Antibody Picoband®
A14175-2 100 µg/Vial

Anti-SERINC2 Antibody Picoband®

Sign In for Pricing
View Details
Anti-Erythropoietin EPO Antibody Picoband®, HRP Conjugate
Bax (2D2), CF568 conjugate, 0.1mg/mL
BNC680004-100 1x 100 µL

Bax (2D2), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details