Amino-PEG3-2G degrader-1 (hydrochloride)
Amino-PEG3-2G degrader-1 hydrochloride is the hydrochloride salt form of Amino-PEG3-2G degrader-1. Amino-PEG3-2G degrader-1 hydrochloride is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 hydrochloride can be used to synthesize autophagy-targeting chimeras (AUTACs).
Product Specifications
UNSPSC
12352005
Target
AUTACs; Autophagy
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg3-2g-degrader-1-hydrochloride.html
Purity
99.04
Smiles
O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCCOCCOCCOCCCN)N=C4)N.Cl
Molecular Formula
C25H34ClFN8O4
Molecular Weight
565.04
References & Citations
[1]Takahashi D, et al. Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023 Sep 14;66 (17) :12342-12372.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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