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GLP-1 (28-36) amide (TFA)

GLP-1 (28-36) amide TFA, a C-terminal nonapeptide of GLP-1, is a major product derived from the cleavage of GLP-1 by the neutral endopeptidase (NEP) . GLP-1 (28-36) amide TFA is an antioxidant and targets to mitochondrion, inhibits mitochondrial permeability transition (MPT) . GLP-1 (28-36) amide TFA has anti-diabetic and cardioprotection effects[1].

Product Specifications

UNSPSC

12352209

Target

GCGR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/glp-1-28-36-amide-tfa.html

Solubility

10 mM in DMSO

Smiles

N=C(N)NCCC[C@@H](C(N)=O)NC(CNC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C56H86F3N15O11

Molecular Weight

1202.37

References & Citations

[1]Bilan Zhou, et al. GLP-1 (28-36) amide, a Long Ignored Peptide Revisited. Open Biochem J. 2014 Dec 31;8:107-11.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3101A/GLP-1-28-36-amide-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3101A/

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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