Isobutylshikonin

Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (HY-D1056) [1].

Product Specifications

CAS Number

[52438-12-7]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isobutylshikonin.html

Purity

99.93

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=CC(O)=C2C(C=C1[C@@H](C/C=C(C)/C)OC(C(C)C)=O)=O

Molecular Formula

C20H22O6

Molecular Weight

358.39

References & Citations

[1] Koike A, et al. Simultaneous Addition of Shikonin and Its Derivatives with Lipopolysaccharide Induces Rapid Macrophage Death. Biol Pharm Bull. 2016;39 (6) :969-76.