Isobutylshikonin
Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS.
Product Specifications
CAS Number
52438-12-7
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isobutylshikonin.html
Purity
99.93
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C2=C(O)C=CC(O)=C2C(C=C1[C@@H](C/C=C(C)/C)OC(C(C)C)=O)=O
Molecular Formula
C20H22O6
Molecular Weight
358.39
References & Citations
[1] Koike A, et al. Simultaneous Addition of Shikonin and Its Derivatives with Lipopolysaccharide Induces Rapid Macrophage Death. Biol Pharm Bull. 2016;39 (6) :969-76.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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