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CD57 / B3GAT1 (NK-1), 0.2mg/mL

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

3-Glucuronyltransferase 1; B3GAT1; Galactosylgalactosylxylosylprotein 3-beta-Glucuronosyltransferase 1; GLCATP; GlcUAT-P; Glucuronosyltransferase P; UDP GlcUA Glycoprotein beta 1, 3 Glucuronyltransferase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

B3GAT1

Gene ID

27087

NCBI Gene ID

381050

UniProt

Q9P2W7

Swiss Prot

Q9P2W7

Host

Mouse

Species Reactivity

Human

Reactivity

B3GAT1|CD57

Immunogen

Human peripheral blood mononuclear cells

Target Antigen

B3GAT1 | CD57

Clonality

Monoclonal

Clone

NK-1

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |IF (published) |IHC, FFPE (verified) |WB (published)

Field of Research

Cancer, Immunology

Positive Control

Lymph node or Tonsil

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

~110 kDa (Glycoprotein)

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Asian J Androl (2010) 12(4): 548-555. (WB blot; Flow) Cancer Immunol Immunother (2011) 60:1683-1695. (Flow, surface) Cancer Sci (2016) 107: 846-852. (IHC, FFPE) Cell Stem Cell (2017) 20(6): 874-890.e7. (IF; Flow, surface)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgM, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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