Antitumor agent-176
Product Specifications
UNSPSC Description
Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM[1].
Target Antigen
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-176.html
Smiles
OC(C1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C=C1)CC(O)(C(F)(F)F)C(F)(F)F
Molecular Weight
430.34
References & Citations
[1]Taranto S, et al. Discovery of novel FGF trap small molecules endowed with anti-myeloma activity[J]. Pharmacological Research, 2024: 107291.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161840/Antitumor-agent-176-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161840/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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