Antitumor agent-176

Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-176.html

Smiles

OC(C1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C=C1)CC(O)(C(F)(F)F)C(F)(F)F

Molecular Formula

C21H16F6O3

Molecular Weight

430.34

References & Citations

[1]Taranto S, et al. Discovery of novel FGF trap small molecules endowed with anti-myeloma activity[J]. Pharmacological Research, 2024: 107291.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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