Antitumor agent-176
Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-176.html
Smiles
OC(C1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C=C1)CC(O)(C(F)(F)F)C(F)(F)F
Molecular Formula
C21H16F6O3
Molecular Weight
430.34
References & Citations
[1]Taranto S, et al. Discovery of novel FGF trap small molecules endowed with anti-myeloma activity[J]. Pharmacological Research, 2024: 107291.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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