Recombinant Human PODXL Protein (GST Tag)
Product Specifications
Background
Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer.
Abbreviation
PODXL
Synonyms
Podocalyxin-like protein; PODXL; Gp200; PC; PCLP; PCLP-1; GCTM-2 antigen; GCTM; Gp200MGC138240; PCLP1; PCpodocalyxin; Podocalyxin; podocalyxin-like; PCLPGCTM-2 antigen; POD XL; Podocalyxin-like protein 1; Gp200; PCLP; PCLP 1; PCLP1; Podocalyxin; podocalyxin like; Podocalyxin like protein 1; PODXL; RCC marker; Renal Cell Carcinoma marker; TRA 1 81; TRA-1-60; GCTM 2 antigen; TRA 1 60
UniProt
O00592
Accession Number
O00592
Expression System
E.coli
Tag
N-GST
Sequence
Ser23-Leu428
Field of Research
Stem Cells; Developmental Biology; Signal Transduction; Cancer; Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 80% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
70.6 kDa
Observed Molecular Weight
78 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Curated Selection
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