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Recombinant Human PODXL Protein (GST Tag)

Product Specifications

Background

Podocalyxin-like protein (PODXL) is a member of CD34 family proteins. It is the protein that carries many post-translational epitopes responsible for various pluripotent surface markers including TRA-1-60, TRA-1-81, GCTM2, GP200, and mAb84.Podocalyxin-like 1 (PODXL) was reported to be closely associated with the development of various cancers.KLF4/PODXL signaling pathway assumes an irreplaceable role in tumorigenesis, invasion and metastasis of human GC and PODXL serves as an independent prognostic indicator for GC patients. PODXL may be a novel, non-invasive diagnostic biomarker for the detection of pancreatic cancer.

Abbreviation

PODXL

Synonyms

Podocalyxin-like protein; PODXL; Gp200; PC; PCLP; PCLP-1; GCTM-2 antigen; GCTM; Gp200MGC138240; PCLP1; PCpodocalyxin; Podocalyxin; podocalyxin-like; PCLPGCTM-2 antigen; POD XL; Podocalyxin-like protein 1; Gp200; PCLP; PCLP 1; PCLP1; Podocalyxin; podocalyxin like; Podocalyxin like protein 1; PODXL; RCC marker; Renal Cell Carcinoma marker; TRA 1 81; TRA-1-60; GCTM 2 antigen; TRA 1 60

UniProt

O00592

Accession Number

O00592

Expression System

E.coli

Tag

N-GST

Sequence

Ser23-Leu428

Field of Research

Stem Cells; Developmental Biology; Signal Transduction; Cancer; Cardiovascular

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method

Purity

> 80% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

70.6 kDa

Observed Molecular Weight

78 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human

Available Sizes

Frequently Asked Questions

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