CD50 / ICAM3 (ICO-60), CF647 conjugate, 0.1mg/mL
Recognizes the N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
Product Specifications
CAS Number
9007-83-4
Synonyms
ICAMR; Intercellular adhesion molecule 3 (ICAM3)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ICAM3
Gene ID
3385
NCBI Gene ID
354563
UniProt
P32942
Swiss Prot
P32942
Host
Mouse
Species Reactivity
Human
Reactivity
CD50
Immunogen
Human ICAM3
Target Antigen
CD50
Clonality
Monoclonal
Clone
ICO-60
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Field of Research
Immunology
Positive Control
HL-60 or THP-1 cells. Lymph node and tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
110-160 kDa
References & Citations
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647
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