CD50 / ICAM3 (ICO-60), Biotin conjugate, 0.1mg/mL

Recognizes the N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

Product Specifications

CAS Number

9007-83-4

Synonyms

ICAMR; Intercellular adhesion molecule 3 (ICAM3)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ICAM3

Gene ID

3385

NCBI Gene ID

354563

UniProt

P32942

Swiss Prot

P32942

Host

Mouse

Species Reactivity

Human

Reactivity

CD50

Immunogen

Human ICAM3

Target Antigen

CD50

Clonality

Monoclonal

Clone

ICO-60

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published)

Field of Research

Immunology

Positive Control

HL-60 or THP-1 cells. Lymph node and tonsil

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

110-160 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. J Gen Virol (1995) 76: 1345-1352. (functional assay) JBC (1996) 271(39): 23920-23927. (Flow, functional assay)