MitoP (bromide)
MitoP bromide is the reaction product of MitoB with H2O2. A high MitoP/MitoB ratio indicates that the mitochondria have a high average level of H2O2[1][2].
Product Specifications
CAS Number
74597-01-6
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mitop-bromide.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=CC=C1.[Br-]
Molecular Formula
C25H22BrOP
Molecular Weight
449.32
References & Citations
[1]Salin K, et al. Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress. Sci Rep. 2017 Jan 24;7:41228.|[2]Cochemé HM, et al. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nat Protoc. 2012 Apr 19;7 (5) :946-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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