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CD48 (5-4.8), Biotin conjugate, 0.1mg/mL

Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI) -anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

B cell membrane protein; B-cell activation marker; BCM1 surface antigen; BLAST1; Signaling lymphocytic activation molecule 2; SLAM family member 2 (SLAMF2) ; TCT.1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD48

Gene ID

962

NCBI Gene ID

243564

UniProt

P09326

Swiss Prot

P09326

Host

Mouse

Species Reactivity

Human

Reactivity

CD48

Immunogen

Human peripheral blood lymphocytes

Target Antigen

CD48

Clonality

Monoclonal

Clone

5-4.8

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |WB (published)

Field of Research

Immunology

Positive Control

Daudi, JY, Raji, Jurkat, and human lymphocytes. Human lymph node and tonsil.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

45 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. J Exp Med (1996) 184: 1769-1779. (functional studies)>/li> J Immunol (2001) 166:5567-5577. (Flow; functional studies; WB)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product Datasheet

https://cdn.gentaur.com/products/37/871988/datasheet/bncb1057-100.pdf

Product MSDS

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

Fragment

IgG2a, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

Biotin

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