Cbl-b-IN-18
Cbl-b-IN-18 (compound 51) is an inhibitor of the E3 ligase Casitas B-lineage lymphoma proto-oncogene B (CPL-B) . Cbl-b-IN-18 inhibits the phosphorylation of CPL-B (IC50[1].
Product Specifications
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=NC(C3CC3)=CC(C4=CC=C(F)C=C4C5=NN=CN5C)=C2)C=NC6=C1C=C(CN7C[C@@H](C)CCC7)C=C6C(F)(F)F
Molecular Formula
C33H31F4N7O
Molecular Weight
617.64
References & Citations
[1]Murugan CHINNAPATTU, et al. Bicyclic heterocyclic compounds as cbl-b inhibitors. Worldwide, WO2024062363A1. 2023-09-18
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR224008L4V 200 µL
Brd3 (NM_001113574) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details MBS2507480-01 24 Tests (Limit 1)
Rat IL-2SRalpha (Soluble Interleukin-2 Receptor) ELISA Kit
Sign In for Pricing
View Details MBS2507480-02 48 Tests
Rat IL-2SRalpha (Soluble Interleukin-2 Receptor) ELISA Kit
Sign In for Pricing
View Details MBS2507480-03 96 Tests
Rat IL-2SRalpha (Soluble Interleukin-2 Receptor) ELISA Kit
Sign In for Pricing
View Details