IU1
IU1 is a special Usp14 inhibitor with an IC50 of 4-5 μM.
Product Specifications
CAS Number
[314245-33-5]
UNSPSC
12352005
Hazard Statement
H318
Target
Autophagy; Deubiquitinase
Type
Reference compound
Related Pathways
Autophagy; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/IU1.html
Purity
99.30
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
CC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3
Molecular Formula
C18H21FN2O
Molecular Weight
300.37
Precautions
H318
References & Citations
[1]Lee BH, et al. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 2010 Sep 9;467 (7312) :179-84.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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