Cholesterol absorption inhibitor 1
Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester[1].
Product Specifications
CAS Number
[190595-65-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cholesterol-absorption-inhibitor-1.html
Purity
98.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=C(F)C=C2)[C@H](C3=CC=C(OCC4=CC=CC=C4)C=C3)[C@H]1CCC(C5=CC=C(F)C=C5)=O
Molecular Formula
C31H25F2NO3
Molecular Weight
497.53
Precautions
H302, H315, H319, H335
References & Citations
[1]S B Rosenblum, et al. Discovery of 1- (4-fluorophenyl) - (3R) -[3- (4-fluorophenyl) - (3S) -hydroxypropyl]- (4S) - (4 -hydroxyphenyl) -2-azetidinone (SCH 58235) : a designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem. 1998 Mar 12;41 (6) :973-80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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