Cholesterol absorption inhibitor 1

Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester[1].

Product Specifications

CAS Number

[190595-65-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cholesterol-absorption-inhibitor-1.html

Purity

98.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1N(C2=CC=C(F)C=C2)[C@H](C3=CC=C(OCC4=CC=CC=C4)C=C3)[C@H]1CCC(C5=CC=C(F)C=C5)=O

Molecular Formula

C31H25F2NO3

Molecular Weight

497.53

Precautions

H302, H315, H319, H335

References & Citations

[1]S B Rosenblum, et al. Discovery of 1- (4-fluorophenyl) - (3R) -[3- (4-fluorophenyl) - (3S) -hydroxypropyl]- (4S) - (4 -hydroxyphenyl) -2-azetidinone (SCH 58235) : a designed, potent, orally active inhibitor of cholesterol absorption. J Med Chem. 1998 Mar 12;41 (6) :973-80.