TCV-309
TCV-309 is an antagonist for platelet activating factor (PAF) . TCV-309 improves the left ventricular function during ischemia-reperfusion (77.6% recover at 1 μM), protects the cardiac function[1].
Product Specifications
CAS Number
131311-25-6
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tcv-309.html
Smiles
CCC[N+]1=CC(C(N(CCC(NCCOC(N2CC3=C(C=CC=C3)CC2)=O)=O)C4=CC=CC=C4)=O)=CC(Br)=C1.[O-][N+]([O-])=O
Molecular Formula
C30H34BrN5O7
Molecular Weight
656.52
References & Citations
[1]Katoh S, et al., Role of platelet activating factor in ischaemia-reperfusion injury of isolated rabbit hearts: protective effect of a specific platelet activating factor antagonist, TCV-309. Cardiovasc Res. 1993 Aug;27 (8) :1430-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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