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5'-Guanylic acid-13C10 (dilithium)

5'-Guanylic acid-13C10 (5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10) dilithium is 13C-labeled 5'-Guanylic acid (HY-N5134) . 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

Product Specifications

Product Name Alternative

5'-GMP-13C10 (dilithium) ; 5'-guanosine monophosphate-13C10 (dilithium)

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5-guanylic-acid-13c10-dilithium.html

Solubility

10 mM in DMSO

Smiles

O=P(O[Li])(O[Li])O[13CH2][13C@H]1O[13C@@H](N2[13C](N=[13C](N)N[13C]3=O)=[13C]3N=[13CH]2)[13C@H](O)[13C@@H]1O

Molecular Formula

13C10H12Li2N5O8P

Molecular Weight

385.01

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

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