Ciprofloxacin (monohydrochloride)
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].
Product Specifications
CAS Number
[93107-08-5]
Product Name Alternative
Bay-09867 (monohydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Apoptosis; Bacterial; Mitochondrial Metabolism; Reactive Oxygen Species (ROS) ; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Ciprofloxacin_hydrochloride.html
Purity
99.90
Solubility
DMSO : 5 mg/mL (ultrasonic) |H2O : 12.5 mg/mL (ultrasonic)
Smiles
[H]Cl.O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCNCC4)=C3)C1=O)O
Molecular Formula
C17H19ClFN3O3
Molecular Weight
367.81
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Citation 01
Available Sizes
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