(S, R, S) -AHPC-O-CF3
(S, R, S) -AHPC-O-CF3 is a ligand for E3 ubiquitinase. (S, R, S) -AHPC-O-CF3 can be used to synthesize PROTAC SMARCA2/4-degrader-20 (HY-163873) [1].
Product Specifications
CAS Number
[2641373-92-2]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-o-cf3.html
Smiles
CC(C)(C)[C@H](N)C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)OC(F)(F)F)=O)=O
Molecular Formula
C23H29F3N4O4S
Molecular Weight
514.56
References & Citations
[1]Ji N, et al., Smarca degraders and uses thereof. US20230072658A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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