Ralfinamide
Ralfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain[1][2].
Product Specifications
CAS Number
133865-88-0
Product Name Alternative
FCE-26742A
UNSPSC
12352005
Hazard Statement
H301
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ralfinamide.html
Purity
99.78
Solubility
DMSO : ≥ 125 mg/mL
Smiles
C[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O
Molecular Formula
C17H19FN2O2
Molecular Weight
302.35
Precautions
H301
References & Citations
[1]Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139 (2) :293-305.|[2]Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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