Human CTSZ Protein

<strong>Human CTSZ Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012075_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cathepsin Z preproprotein protein, Cathepsin Z protein, CTSX protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Huang M, Modeste E, Dammer E, Merino P, Taylor G, Duong DM, Deng Q, Holler CJ, Gearing M, Dickson D, Seyfried NT, Kukar T. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations Acta Neuropathol Commun. 2020 Oct 7;8(1):163._x000D_ 2: Batista AAS, Franco BM, Perez MM, Pereira EG, Rodrigues T, Wroclawski ML, Fonseca FLA, Suarez ER. Decreased levels of cathepsin Z mRNA expressed by immune blood cells: diagnostic and prognostic implications in prostate cancer Braz J Med Biol Res. 2021 Aug 6;54(10):e11439._x000D_ 3: Dolenc I, Štefe I, Turk D, Taler-Verčič A, Turk B, Turk V, Stoka V. Human cathepsin X/Z is a biologically active homodimer Biochim Biophys Acta Proteins Proteom. 2021 Feb;1869(2):140567._x000D_ 4: Cooke GS, Campbell SJ, Bennett S, Lienhardt C, McAdam KP, Sirugo G, Sow O, Gustafson P, Mwangulu F, van Helden P, Fine P, Hoal EG, Hill AV. Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis Am J Respir Crit Care Med. 2008 Jul 15;178(2):203-7._x000D_ 5: Cai X, Gao C, Song H, Yang N, Fu Q, Tan F, Li C. Characterization, expression profiling and functional characterization of cathepsin Z (CTSZ) in turbot (Scophthalmus maximus L.) Fish Shellfish Immunol. 2019 Jan;84:599-608._x000D_ 6: Adams LA, Möller M, Nebel A, Schreiber S, van der Merwe L, van Helden PD, Hoal EG. Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility Eur J Hum Genet. 2011 Jun;19(6):676-81._x000D_ 7: Wang J, Chen L, Li Y, Guan XY. Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma PLoS One. 2011;6(9):e24967._x000D_ 8: Shen Y, Su Y, Silva FJ, Weller AH, Sostre-Colón J, Titchenell PM, Steger DJ, Seale P, Soccio RE. Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function Cell Rep. 2020 Mar 3;30(9):3079-3091.e5._x000D_ 9: Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects Pharmacol Res. 2021 Dec;174:105935._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29795304">10: Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M. NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population Sci Rep. 2018 May 23;8(1):8071. </a>_x000D_ _x000D_ <strong>Products Related to Human CTSZ Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>