BI-11634
BI-11634 is a factor Xa inhibitor. BI-11634 is metabolized by CYP3A4 to form one major metabolite and this reaction is inhibited by Quinidine with a Ki of 7 µM[1].
Product Specifications
CAS Number
1622159-00-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bi-11634.html
Smiles
O=C(C1=CC=C(C(C)=C1)N2C(COCC2)=O)N[C@@H](COC)C3=NC4=CC=C(C=C4[N-]3)Cl.[Na+]
Molecular Formula
C22H22ClN4NaO4
Molecular Weight
464.88
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Mathur A, et al. Unexpected interaction between CYP3A4 and BI 11634: is BI 11634 interacting with CYP3A4 similar to nifedipine? Drug Metabol Drug Interact. 2013;28 (4) :239-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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