CD73-IN-16
CD73-IN-16 (compound 18) is an inhibitor of hCD73 with IC50 values of 0.28 μM[1].
Product Specifications
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd73-in-16.html
Smiles
ClC(C=N1)=CC2=C1NN=C2C3=CC=C4C(COC(C(O)=O)(C(O)=O)CC5=CC=CC=C5)=NNC4=C3
Molecular Formula
C24H18ClN5O5
Molecular Weight
491.88
References & Citations
[1]Cunjian Shi, et al. Design, synthesis and structure-activity relationship of malonic acid non-nucleoside derivatives as potent CD73 inhibitors. Bioorg Med Chem Lett. 2024 Nov 1:112:129946.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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