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CD73-IN-16

CD73-IN-16 (compound 18) is an inhibitor of hCD73 with IC50 values of 0.28 μM[1].

Product Specifications

UNSPSC

12352005

Target

CD73

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cd73-in-16.html

Smiles

ClC(C=N1)=CC2=C1NN=C2C3=CC=C4C(COC(C(O)=O)(C(O)=O)CC5=CC=CC=C5)=NNC4=C3

Molecular Formula

C24H18ClN5O5

Molecular Weight

491.88

References & Citations

[1]Cunjian Shi, et al. Design, synthesis and structure-activity relationship of malonic acid non-nucleoside derivatives as potent CD73 inhibitors. Bioorg Med Chem Lett. 2024 Nov 1:112:129946.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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