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Anti-Mouse CD27 Antibody (RM27-3E5)

Anti-Mouse CD27 Antibody (RM27-3E5) is an agonistic rat-derived IgG2a κ type antibody, targeting to mouse CD27. Anti-Mouse CD27 Antibody (RM27-3E5) stimulates CD 27. Anti-Mouse CD27 Antibody (RM27-3E5) can be used for the researches of cancer and immunology, such as B16cOVA tumor[1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

TNF Receptor; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd27-antibody-rm27-3e5.html

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD27Antibody(RM27-3E5)]

Molecular Weight

(150 kDa)

References & Citations

[1]Roberts DJ, et al. Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8 (+) T cells. J Immunother. 2010 Oct;33 (8) :769-79.|[2]Ahrends T, et al. CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination. Cancer Res. 2016 May 15;76 (10) :2921-31.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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