WWP1/2-IN-1
WWP1/2-IN-1 (compound 11) is a WWP1/2 inhibitor with the IC50 values of 32.7µM and 269.2µM for WWP1 and WWP2, respectively[1].
Product Specifications
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wwp1-2-in-1.html
Smiles
CCOC(CCCSC1=NC2=C(N1)N=C(C(Cl)=N2)Cl)=O
Molecular Formula
C11H12Cl2N4O2S
Molecular Weight
335.21
References & Citations
[1]Dudey AP, et al. Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases. J Enzyme Inhib Med Chem. 2024 Dec;39 (1) :2394895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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