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BI-167107

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM[1].

Product Specifications

CAS Number

[1202235-68-4]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/bi-167107.html

Concentration

10mM

Purity

99.61

Solubility

DMSO : 75 mg/mL (ultrasonic)

Smiles

O=C1NC(C(O)=CC=C2C(O)CNC(C)(CC3=C(C=CC=C3)C)C)=C2OC1

Molecular Formula

C21H26N2O4

Molecular Weight

370.44

References & Citations

[1]Rasmussen SG, et al. Structure of a nanobody-stabilized active state of the β (2) adrenoceptor. Nature. 2011 Jan 13;469 (7329) :175-80.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

β adrenergic receptor

Available Sizes

Curated Selection

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