1-Cbz-azetidine-3-carboxylic acid
1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]</sup
Product Specifications
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-cbz-azetidine-3-carboxylic-acid.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C(=O)(OCC1=CC=CC=C1)N2CC(C2)C(=O)O
Molecular Formula
C12H13NO4
Molecular Weight
235.24
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W004868/1-Cbz-azetidine-3-carboxylic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W004868/1-Cbz-azetidine-3-carboxylic-acid-SDS-MedChemExpress.pdf
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
CAS Number
[97628-92-7]
Available Sizes
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