ICAM-1988
ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity[1].
Product Specifications
CAS Number
[444169-80-6]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/icam-1988.html
Smiles
O=C([C@@H](NC(C1=C(C=C(C=C1Cl)CNC(/C=C/C2=CC=CO2)=O)Cl)=O)CNC([C@H]3NCSC3)=O)O
Molecular Formula
C22H22Cl2N4O6S
Molecular Weight
541.40
References & Citations
[1]Khojasteh SC, et al. Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug. Xenobiotica. 2008 Mar;38 (3) :340-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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