ICAM-1988

ICAM-1988 is a small molecule lymphocyte function-associated antigen-1 (LFA-1) antagonist that disrupts the LFA-1/ICAM-1 interaction and has anti-inflammatory activity[1].

Product Specifications

CAS Number

[444169-80-6]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/icam-1988.html

Smiles

O=C([C@@H](NC(C1=C(C=C(C=C1Cl)CNC(/C=C/C2=CC=CO2)=O)Cl)=O)CNC([C@H]3NCSC3)=O)O

Molecular Formula

C22H22Cl2N4O6S

Molecular Weight

541.40

References & Citations

[1]Khojasteh SC, et al. Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug. Xenobiotica. 2008 Mar;38 (3) :340-52.