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Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) (rIG266), CF740 conjugate, 0.1mg/mL

Recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

G1m Marker | G2m Marker | G3m Marker | G4m Marker | HDC | Heavy Chain Disease Protein | Human Immunglobulin G | Ig gamma1/2/3/4 Chain C Region | IGHG1 | IGHG2 | IGHG3 | IGHG4 | Immunoglobulin Heavy Constant 1/2/3/4

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

IGHG

Gene ID

3500; 3501; 3502; 3503

NCBI Gene ID

510635

UniProt

P01857, P01859, P01860, P01861

Swiss Prot

P01857, P01859, P01860, P01861

Host

Mouse

Species Reactivity

Human

Reactivity

IgG

Immunogen

Recombinant full-length human IGHG protein

Target Antigen

IgG

Clonality

Recombinant Monoclonal

Clone

RIG266

Type

Anti-Human Immunoglobulin|Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Immunology, Inflammation

Positive Control

293T, Raji or hPBL cells. Tonsil or Spleen

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% rBSA, 0.05% azide

Molecular Weight

75 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), Bos taurus (bovine)

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF740

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