(S, R, S) -AHPC-PEG2-C5-N3
(S, R, S) -AHPC-PEG2-C5-N3 is a synthesized E3 ligase ligand-linker conjugate. (S, R, S) -AHPC-PEG2-C5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups[1].
Product Specifications
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-peg2-c5-n3.html
Smiles
O=C([C@@H]1C[C@@H](O)CN1C([C@H](C(C)(C)C)NC(COCCOCCNC(CCCCCN=[N+]=[N-])=O)=O)=O)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Molecular Formula
C34H50N8O7S
Molecular Weight
714.88
References & Citations
[1]Yang B, et al. Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3. Bioorg Med Chem Lett. 2024 Nov 1;112:129945.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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