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Rel- (R, R) -THC

Rel- (R, R) -THC is the relative configuration of (R, R) -THC. (R, R) -THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R, R) -THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6[1].

Product Specifications

CAS Number

138090-06-9

UNSPSC

12352005

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/rel-r-r-thc.html

Smiles

CC[C@H]1C2=C([C@@H](CC3=CC(O)=CC=C32)CC)C4=CC=C(O)C=C4C1

Molecular Formula

C22H24O2

Molecular Weight

320.42

References & Citations

[1]Sun J, et al. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology. 1999;140 (2) :800-804.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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