Rel- (R, R) -THC
Rel- (R, R) -THC is the relative configuration of (R, R) -THC. (R, R) -THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R, R) -THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6[1].
Product Specifications
CAS Number
138090-06-9
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rel-r-r-thc.html
Smiles
CC[C@H]1C2=C([C@@H](CC3=CC(O)=CC=C32)CC)C4=CC=C(O)C=C4C1
Molecular Formula
C22H24O2
Molecular Weight
320.42
References & Citations
[1]Sun J, et al. Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta. Endocrinology. 1999;140 (2) :800-804.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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