Anti-Hu CD303 Purified
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Product Specifications
Certification
RUO
Immunogen
CD303 ectodomain fused with human IgG Fc domain
Target Antigen
CD303
Clone
15E3
Applications
ICC, ELISA, FC, IHC-F
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1 kappa
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