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Anti-Hu CD303 Purified

CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

CD303 ectodomain fused with human IgG Fc domain

Target Antigen

CD303

Clone

15E3

Applications

ICC, ELISA, FC, IHC-F

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.

Applications Notes

Flow cytometry: Recommended dilution: 1-5 μg/ml.

Isotype

Mouse IgG1 kappa

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