DBM-GGFG-NH-O-CO-Exatecan
DBM-GGFG-NH-O-CO-Exatecan is an inhibitor for topoisomerase I. DBM-GGFG-NH-O-CO-Exatecan can be used as a drug-linker conjugate for synthesis of ADC molecule[1].
Product Specifications
CAS Number
[2769152-95-4]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbm-ggfg-nh-o-co-exatecan.html
Purity
96.83
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C(Br)=C(C1=O)Br)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
Molecular Formula
C52H54Br2FN9O13
Molecular Weight
1191.84
References & Citations
[1]Song Y, et al., Antibody conjugate intermediate and preparation method therefor. WO2022099762.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Curated Selection
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